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Howard Brown has a long tradition of participating in nationally funded research initiatives. During the 1970's, Howard Brown gained national prominence through its involvement in a research study that led to the development of the Hepatitis B vaccine.

In 1983, Howard Brown again achieved widespread acclaim when it was chosen by the National Institutes of Health to participate in the Multi-site AIDS Cohort Study (MACS), a large-scale study of the natural history of AIDS in gay and bisexual men.

The MACS continues today and is the largest epidemiological study in the world on sexual practices and how they relate to the transmission of HIV. Howard Brown Health Center also collaborated on the AIDS Epidemiological Study, funded by The Centers for Disease Control (CDC), between 1987 and 1992 and Vaccine Preparedness studies in 1995.

Currently, Howard Brown is receiving funding from the CDC to participate in Project iCARE, a behavioral intervention study. Participants in iCARE are African American men who have sex with men who also use substances while engaging in high risk sexual behaviors. The study grew out of earlier studies such as Project MIX by building in a substantial cultural component. Also funded through CDC and running concurrently is Life Skills. This study will develop and pilot test a ground-breaking HIV prevention intervention for young trans women.

Since 2000, Howard Brown has expanded into clinical research, with experience in more than 20 clinical research trials, ranging from Phase I to Phase IV. Howard Brown is currently running 13 clinical research studies, including investigational prevention vaccinations, device studies, and active treatment of LGBT primary care concerns.

Howard Brown research is expanding into other areas of LGBT health. We are currently running two new studies testing cancer prevention strategies for men and women. Other areas of research will include smoking cessation and the development of a patient navigation curriculum.

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